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Bacterial Proteins / physiology. Biomedical Research / trends. Child, Preschool. Humans. Moraxella catarrhalis / immunology. Moraxella catarrhalis / pathogenicity*. Moraxellaceae Infections / microbiology*. Respiratory Tract Infections / microbiology*. Virulence. Virulence Factors / physiology*.

It was first described at the end of the nineteenth century when it was named Micrococcus catarrhalis, and it was later changed to Neisseria catarrhalis because of its similarity in phenotype and ecological niche to 2000-04-01 Virulence factor. Virulence factors are molecules produced by bacteria, viruses, fungi, and protozoa that add to their effectiveness and enable them to achieve the following. New!!: Moraxella catarrhalis and Virulence factor · See more » Virulence-related outer membrane protein family 1995-06-01 · In young children (age 4-5 years), the proportion of complement-resistant strains was around 50%. Complement resistance in B. catarrhalis is associated with illness and may hence be considered a virulence factor. Keywords: Branhamella; Complement resistance; Moraxella; Respiratory tract; Virulence 1. 1990-05-14 · The lipopolysaccharide and outer membrane proteins of B. catarrhalis have been characterized and found to be relatively non-varying among different strains. Circumstantial evidence exists in support of the hypothesis that the B. catarrhalis beta-lactamase is a virulence determinant.

Branhamella catarrhalis virulence factors

complement resistance. Virulence factors As an important repiratory pathogen, M.(B). catarrhalis is armed with numerous virulence factors to allow its invasion and colonization of human respiratory tract. Several of these factors have been identified and characterized in the last decade including Complement resistance in B. catarrhalis is associated with illness and may hence be considered a virulence factor.

1 Oct 2004 Moraxella catarrhalis ubiquitous surface protein A2 (UspA2) mediates resistance Complement resistance is a virulence factor of Branhamella

1995-06-01 Complement resistance is a virulence factor of Branhamella (Moraxella) catarrhalis Cees Hol Eijkman‐Winkler Institute for Medical and Clinical Microbiology, University Hospital, Room G04.614, P.O. Box 85,500, NL‐3508 GA Utrecht, The Netherlands M. catarrhalis, earlier called Branhamella catarrhalis, is a smart pathogen, gaining significance as a pathogen over few decades, and having an array of virulence factors, of which biofilm formation and lipase and serum or complement resistance are important.12,13 This bacterium is an exclusively human pathogen causing Lower K T Nguyen, E J Hansen, M A Farinha, Construction of a genomic map of Moraxella (Branhamella) catarrhalis ATCC 25238 and physical mapping of virulence-associated genes , Canadian Journal of Microbiology, 10.1139/w99-005, 45, 4, (299-303), (1999). Purpose of review: Moraxella catarrhalis is an emerging human-specific pathogen responsible for upper and lower respiratory tract infections. Understanding the events in the complex pathogenesis and underlying mechanisms during M. catarrhalis infection is a … Comparison of Moraxella catarrhalis isolates from children and adults for growth on modified New York City medium and potential virulence factors.

In young children (age 4–5 years), the proportion of complement-resistant strains was around 50%. Complement resistance in B. catarrhalis is associated with illness and may hence be considered a virulence factor.

Purpose of review: Moraxella catarrhalis is an emerging human-specific pathogen responsible for upper and lower respiratory tract infections. Understanding the events in the complex pathogenesis and underlying mechanisms during M. catarrhalis infection is a key to the development of novel therapeutics and vaccines. Genomic and Metabolic Studies 1687 Virulence Factors 1690 Immune Response and Vaccine Development 1693 Conclusion 1693 References 1693 In the late 1960s, reports of the isolation of N. catarrhalis as a pathogen re- emerged (Coffey et al., 1967; Feign et al., 1969) and these continued to increase during the 1970s.

1995-06-01 It is largely unknown if virulence is associated with particular strains or subpopulations of M. catarrhalis, or if differences in clinical manifestation can be attributed to the heterogeneous expression of specific M. catarrhalis virulence factors in the circulating population. 1995-06-01 Complement resistance is a virulence factor of Branhamella (Moraxella) catarrhalis Cees Hol Eijkman‐Winkler Institute for Medical and Clinical Microbiology, University Hospital, Room G04.614, P.O. Box 85,500, NL‐3508 GA Utrecht, The Netherlands M. catarrhalis, earlier called Branhamella catarrhalis, is a smart pathogen, gaining significance as a pathogen over few decades, and having an array of virulence factors, of which biofilm formation and lipase and serum or complement resistance are important.12,13 This bacterium is an exclusively human pathogen causing Lower K T Nguyen, E J Hansen, M A Farinha, Construction of a genomic map of Moraxella (Branhamella) catarrhalis ATCC 25238 and physical mapping of virulence-associated genes , Canadian Journal of Microbiology, 10.1139/w99-005, 45, 4, (299-303), (1999). Purpose of review: Moraxella catarrhalis is an emerging human-specific pathogen responsible for upper and lower respiratory tract infections. Understanding the events in the complex pathogenesis and underlying mechanisms during M. catarrhalis infection is a … Comparison of Moraxella catarrhalis isolates from children and adults for growth on modified New York City medium and potential virulence factors. El-Ahmer OR(1), Braun JM, Amyes SG, Weir DM, Beuth J, … Since M. catarrhalis has been considered a harmless commensal bacterium for a long time, there is relatively little cognition about pathogenicity characteristics and its virulence factors. Generally, the pathogenicity of this bacterium, like other microorganisms, depends on the ability to escape from the host defense mechanisms and binding to cellular and mucus layer, as well ( 4 ).
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Moraxella Catarrhalis is very common in infants and young children, mostly causing otitis media (ear infections). Over 15 to 20% of all cases of otitis media are caused by Moraxella. It is also found in around 2 to 4 million people that suffer from chronic obstructive pulmonary disease.

Recently, we showed that complement resistance is an important virulence factor of Moraxella (Branhamella) catarrhalis. Our study used a serum bactericidal assay to determine complement resistance in M. catarrhalis. Perez Vidakovics, Laura and Kristian Riesbeck.
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K T Nguyen, E J Hansen, M A Farinha, Construction of a genomic map of Moraxella (Branhamella) catarrhalis ATCC 25238 and physical mapping of virulence-associated genes , Canadian Journal of Microbiology, 10.1139/w99-005, 45, 4, (299-303), (1999).

Branhamella , Complement resistance , Moraxella , Respiratory tract , Virulence References The complement system is an important innate defence mechanism, and the ability to resist complement-mediated killing is considered a key virulence trait of the respiratory tract pathogen M. catarrhalis. Virulence factors As an important repiratory pathogen, M.(B). catarrhalis is armed with numerous virulence factors to allow its invasion and colonization of human respiratory tract. Several of these factors have been identified and characterized in the last decade including Se hela listan på antimicrobe.org explained by the high carriage rates of Moraxella (Branhamella) catarrhalis in this age group. Nosocomial infections by this organism are also evident (Wright et al., 1990). 1.4 Virulence factors As Moraxella (Branhamella) catarrhalis becomes more widely accepted as a pathogen, it is important to begin to identify potential virulence factors of Since M. catarrhalis has been considered a harmless commensal bacterium for a long time, there is relatively little cognition about pathogenicity characteristics and its virulence factors. Generally, the pathogenicity of this bacterium, like other microorganisms, depends on the ability to escape from the host defense mechanisms and binding to cellular and mucus layer, as well ( 4 ).

M. catarrhalis has a range of virulence factors, which allow the bacterium to adhere to host epithelial cells, enter host tissues, successfully multiply, interfere with and avoid host defence

mophilus influenzae och framför allt Moraxella catarrhalis mer kan likna en SOM, ibland beta-lactamase-mediated resistance to beta-lactams: aspects of virulence and treatment. Risk factors for chronic otitis media with effusion in infancy.

Our study used a serum bactericidal assay to determine complement resistance in M. catarrhalis. Although the serum bactericidal Virulence Factors: physiology, Respiratory Tract Infections: microbiology, Moraxellaceae Infections: microbiology, Moraxella (Branhamella) catarrhalis: pathogenicity, Moraxella (Branhamella) catarrhalis: immunology, Bacterial Proteins: physiology, Biomedical Research: trends in Current Opinion in Infectious Diseases volume 22 issue 3 pages 279 Assessment of complement-mediated killing of Moraxella (Branhamella) catarrhalis isolates by a simple method more by Kees Verduin and Margriet Jansze Recently, we showed that complement resistance is an important virulence factor of Moraxella (Branhamella) catarrhalis. Study 03 - Gram Negative Cocci - Microbes 28 through 30 flashcards from James Ozorkiewicz's class online, or in Brainscape's iPhone or Android app.